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Lambda Light Chain Antibody (ICO-106), Alexa Fluor™ 532, Novus Biologicals™
SDP

Catalog No. NP233308A32 Shop All R&D Systems Products
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NP233308A32 0.1 mL
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Catalog No. NP233308A32 Supplier Novus Biologicals Supplier No. NBP233308AF532
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Description

Mouse Monoclonal Antibody

Lambda Light Chain Monoclonal specifically detects Lambda Light Chain in Human samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Lambda Light Chain
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone ICO-106
Conjugate Alexa Fluor 532
Dilution Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias IGLC, immunoglobulin lambda constant group
Gene Symbols IGLC1
Host Species Mouse
Immunogen Human IgG was used as immunogen to generate the Lambda antibody.
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 3537.0
Test Specificity This monoclonal antibody is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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