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Lambda Light Chain Antibody (ICO-106), Biotin, Novus Biologicals™
SDP

Catalog No. NBP233308B Shop All R&D Systems Products
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NBP233308B 0.1 mL
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Catalog No. NBP233308B Supplier Novus Biologicals Supplier No. NBP233308B
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Description

Mouse Monoclonal Antibody

Lambda Light Chain Monoclonal specifically detects Lambda Light Chain in Human samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Lambda Light Chain
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone ICO-106
Conjugate Biotin
Dilution Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias IGLC, immunoglobulin lambda constant group
Gene Symbols IGLC1
Host Species Mouse
Immunogen Human IgG was used as immunogen to generate the Lambda antibody.
Molecular Weight of Antigen 22.5 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3536
Test Specificity This monoclonal antibody is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Target Species Human
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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