Invitrogen™ Laminin alpha-3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552665

Catalog No. PIPA552665

Description

Immunogen sequence: LLNRIRTWQK THQGENNGLA NSIRDSLNEY EAKLSDLRAR LQEAAAQAKQ ANGLNQENER ALGAIQRQVK EINSLQSDFT KYLTTADSSL LQTNIALQLM EKSQKEYE Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 71%.

Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.

Specifications

• Antigen: Laminin alpha-3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LAMA3
• Gene Alias: [a]3B; BM600; BM600 150kD subunit; E170; Epiligrin; Epiligrin 170 kDa subunit; epiligrin alpha 3 subunit; epiligrin subunit alpha; kalinin 165kD subunit; kalinin subunit alpha; LAM3, alpha-3 subunit; Lama3; Lama3B; laminin 5 alpha 3; laminin 5, alpha-3 subunit; laminin A3; laminin subunit alpha 3; laminin subunit alpha-3; laminin, alpha 3; laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin); Laminin-5; laminin-5 alpha 3 chain; laminin-5 subunit alpha; Laminin-6 subunit alpha; laminin-7 subunit alpha; LAMNA; LOCS; nicein 150kD subunit; nicein subunit alpha; nicein, 150kDa
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3909
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q16787
• Gene Symbols: LAMA3
• Immunogen: Recombinant protein corresponding to Human Laminin alpha-3. Recombinant protein control fragment (Product #RP-89598).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG