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Invitrogen™ LanthaScreen™ Tb-pERM (pLRRKtide) Antibody Kit
A phospho specific antibody directed to the ezrin/radixin/moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants.
Supplier: Invitrogen™ PV4899
Description
A phospho specific antibody directed to the ezrin/radixin/moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease.
For use in combination with the Fluorescein-ERM (LRRKtide) substrate (Cat. No. PV4901) to evaluate inhibitors in medium to high throughput screening applications.
Specifications
| Tb (Terbium)/FITC | |
| 120892 | |
| 150,000 Da | |
| 384-well Plate | |
| Human | |
| End Point | |
| LRRK2 D1994A, LRRK2 R1441C, LRRK2 I2020T, LRRK2 G2019S, LRRK2 | |
| TR-FRET | |
| LanthaScreen™ |
| 25 μg | |
| Terbium-labeled anti-ERM [pLRRKtide] antibody in HEPES buffered saline. Store at -20°C. | |
| Biochemical terbium phospho-specific activity | |
| 340/490, 520 nm | |
| Dry Ice | |
| Hu | |
| Serine/Threonine Kinases | |
| LRRK2 |
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Product Title
For Research Use Only. Not for use in diagnostic procedures.
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