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LEDGF/p75 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501558604
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10 μL
Catalog No. Quantity
50-155-8604 10 μL
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Catalog No. 50-155-8604

Supplier: Bethyl Laboratories, Inc A300847AT

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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Cat

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.

Specifications

Antigen LEDGF/p75
Applications Immunohistochemistry, Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene PSIP1
Gene Accession No. O75475, Q99JF8
Gene Alias CLL-associated antigen KW-7, dense fine speckles 70 kDa protein, DFS 70, DFS70, LEDGF, lens epithelium-derived growth factor, p52, p75, PAIP, PC4 and SFRS1 interacting protein 2, PSIP2, transcriptional coactivator p52/p75, Transcriptional coactivator p75/p52
Gene Symbols Psip1
Host Species Rabbit
Immunogen Between 225 and 275
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101739, 11168
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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