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Levetiracetam, Tocris Bioscience™

Catalog No. 283950
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Antiepileptic; binds SV2A

Levetiracetam is an antiepileptic that displays distinctive properties from conventional antiepileptic drugs. Displays potent seizure protection in animal models of chronic epilepsy but lacks activity in acute seizure models. Binds synaptic vesicle protein 2A (SV2A) and inhibits Na+-dependent Cl-/HCO3- exchange. In a mouse model of Alzheimer's disease, Levetiracetam rescues levels of presynaptic vesicle fusion and neurotransmitter release, reduces Aβ42 and APP levels and decreases deposits of amyloid plaque; in vitro Levetiracetam inhibits Aβ-induced glutamate from astrocytes.

Chemical Identifiers

CAS 102767-28-2
Molecular Formula C8H14N2O2
Molecular Weight (g/mol) 170.21
MDL Number MFCD03265610
InChI Key HPHUVLMMVZITSG-ZCFIWIBFSA-N
Synonym levetiracetam, keppra, s-2-2-oxopyrrolidin-1-yl butanamide, keppra xr, 2s-2-2-oxopyrrolidin-1-yl butanamide, levetiracetamum, ucb-l 059, ucb l059, levetiractam, levroxa
PubChem CID 5284583
ChEBI CHEBI:6437
IUPAC Name (2R)-2-(2-oxopyrrolidin-1-yl)butanamide
SMILES CC[C@@H](N1CCCC1=O)C(N)=O

Specifications

Quantity 50 mg
Formula Weight 170.21
Percent Purity >99%
Chemical Name or Material Levetiracetam

Safety and Handling

Recommended Storage Store at Room Temperature
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