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Lewis A Blood Group Antigen Antibody (SPM522) - IHC-Prediluted, Novus Biologicals™
SDP

Catalog No. NBP248080 Shop All R&D Systems Products
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NBP248080 7 mL
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Catalog No. NBP248080 Supplier Novus Biologicals Supplier No. NBP248080
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Description

Mouse Monoclonal Antibody

Lewis A Blood Group Antigen Monoclonal specifically detects Lewis A Blood Group Antigen in Human, Mouse samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Lewis A Blood Group Antigen
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPM522
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias A transferase, A3GALNT, A3GALT1, ABO, B transferase, EC=2.4.1.37, EC=2.4.1.40, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, GTB, Histo-blood group A transferase, Histo-blood group ABO system transferase, Histo-blood group B transferase, NAGAT
Gene Symbols ABO
Host Species Mouse
Immunogen Mucins isolated from ovarian cyst fluid
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Target Species Human, Mouse
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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