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Invitrogen™ LGP2 Polyclonal Antibody
Rabbit Polyclonal Antibody
$589.50
Specifications
| Antigen | LGP2 |
|---|---|
| Concentration | 0.20 mg/mL |
| Content And Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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PIPA5110841
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Invitrogen™
PA5110841 |
100 μL |
Each for $589.50
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PIPA5110851
|
Invitrogen™
PA5110851 |
100 μL |
Each for $589.50
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Description
Immunogen sequence: GLLTNEISMV QARGRARADQ SVYAFVATEG SRELKRELIN EALETLMEQA VAAVQKMDQA EYQAKIRDLQ QAALTKRAAQ AAQRENQRQQ FPVEHVQLLC INCMVAV.
Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.Specifications
| LGP2 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human | |
| DHX58 | |
| B430001I08Rik; D11LGP2; D11lgp2e; DEXH (Asp-Glu-X-His) box polypeptide 58; DEXH-box helicase 58; DHX58; Lgp2; LPG2; ortholog of mouse D11lgp2; probable ATP-dependent helicase LGP2; Probable ATP-dependent RNA helicase DHX58; protein D11Lgp2; Protein D11Lgp2 homolog; RGD1310093; RIG-I-like receptor 3; RIG-I-like receptor Lgp2; RLR; RLR-3; RNA helicase LGP2 | |
| DHX58 | |
| Primary | |
| Antigen Affinity Chromatography |
| 0.20 mg/mL | |
| Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q96C10 | |
| 79132 | |
| Recombinant Protein corresonding to Human LGP2. Recombinant protein control fragment (Product #RP-92404). | |
| Antibody |
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