Invitrogen™ LIPC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537375

Catalog No. PIPA537375

Description

This antibody detects endogenous protein at a molecular weight of 56 kDa. Purity is >95% by SDS-PAGE.

The Lipase family belongs to one of the most robust genetic superfamilies found in living organisms that includes esterases and thioesterases. Lipase gene products are related by tertiary structure rather than primary amino acid sequence. Balancing the composition and the transport of lipoproteins in human plasma is essential for normal body function and is mediated in part by Hepatic Lipase, also known as HL or LIPC. Rare deficiencies in Hepatic Lipase have been identified in humans which lead to pathologic levels of circulating lipoprotein particles; this condition is associated with coronary artery disease (CAD). Hepatic Lipase is regulated by thyroid hormones and has a dual function as a triglyceride hydrolase and a ligand/bridging factor for receptor-mediated lipoprotein uptake. Hepatic Lipase localizes to the endothelial surfaces of extrahepatic tissues.

Specifications

• Antigen: LIPC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LIPC
• Gene Alias: AI256194; HDLCQ12; hepatic lipase; hepatic triacylglycerol lipase; HL; Hpl; HTGL; lipase C; lipase C, hepatic type; lipase member C; lipase, hepatic; LIPC; LIPH; Triacylglycerol lipase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3990
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P11150
• Gene Symbols: LIPC
• Immunogen: Recombinant full length human LIPC.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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