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Invitrogen™ LRRC15 Polyclonal Antibody
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Catalog No. PIPA5113927
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Quantity:
100 μL
Catalog No. Quantity
PIPA5113927 100 μL
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Catalog No. PIPA5113927

Supplier: Invitrogen™ PA5113927

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Rabbit Polyclonal Antibody

Immunogen sequence: LNISALIALR IEKNELSRIT PGAFRNLGSL RYLSLANNKL QVLPIGLFQG For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%.

Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRC15
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene LRRC15
Gene Accession No. Q8TF66
Gene Alias 5430427N11Rik; hLib; leucine rich repeat containing 15; Leucine-rich repeat protein induced by amyloid-beta; leucine-rich repeat protein induced by beta amyloid; leucine-rich repeat protein induced by beta-amyloid; leucine-rich repeat protein induced by beta-amyloid homolog; Leucine-rich repeat-containing protein 15; LIB; Lrrc15; rLib
Gene Symbols LRRC15
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N terminal region of human LRRC15 (aa 74-123).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 131578
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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