Invitrogen™ LRRC4C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5111400

Catalog No. PIPA5111400

Description

Immunogen sequence: NVDDEITGDT PMESHLPMPA IEHEHLNHYN SYKSPFNHTT TVNTINSIHS SVHEPLLIRM NSKD.

Leucine-rich repeat-containing 4C (LRRC4C), also known as Netrin-G ligand 2 (NGL-2), is a gene highlighted for its expression in the nervous system, particularly the brain. It is a member of the leucine-rich repeat superfamily, which plays a significant role in cell adhesion and signaling pathways critical for synaptic connectivity and neuronal development. LRRC4C is involved in neural processes such as axon guidance and synapse formation, aiding in the establishment of functional neural circuits. Additionally, research has suggested that LRRC4C may function as a tumor suppressor, particularly in gliomas, indicating its potential role in neuro-oncological disorders. Variations or deletions in this gene have been linked to neurodevelopmental disorders, demonstrating its importance in normal brain function and development. Furthermore, LRRC4C's expression patterns and associations with cancer also suggest its potential as a prognostic marker in clinical settings.

Specifications

• Antigen: LRRC4C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRRC4C
• Gene Alias: 6430556C10Rik; KIAA1580; leucine rich repeat containing 4C; leucine-rich repeat-containing protein 4C; Lrrc4c; Netrin-G1 ligand; NGL1; NGL-1; RGD1311013; UNQ292/PRO331
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57689
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.20 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9HCJ2
• Gene Symbols: LRRC4C
• Immunogen: Recombinant Protein corresonding to Human LRRC4C. Recombinant protein control fragment (Product #RP-106572).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov