LRWD1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-156-1183	Bethyl Laboratories, Inc A301868AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt.

Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.

Specifications

• Antigen: LRWD1
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: CENP-33, ORCA, ORC-associated protein, centromere protein 33, leucine-rich repeat and WD repeat-containing protein 1, origin recognition complex associated, origin recognition complex-associated protein
• Immunogen: Between 432 and 482
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: LRWD1

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q8BUI3, Q9UFC0
• Gene ID (Entrez): 222229, 71735
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody