Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. Invitrogen™ LSR Monoclonal Antibody (C2)

Invitrogen™ LSR Monoclonal Antibody (C2)

Catalog No. PIMA543671
Change view
Click to view available options
Quantity:
20 μL
200 μL
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA543671 20 μL
PIMA541630 200 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. PIMA543671 Supplier Invitrogen™ Supplier No. MA543671
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Mouse Monoclonal Antibody

LSR Monoclonal Antibody for Western Blot, IHC (P)

Lipolysis-stimulated lipoprotein receptor (LSR), encoded by the LSR gene, is a crucial component in lipid metabolism, particularly involved in the endocytosis of triglyceride-rich lipoproteins. It is typically expressed in liver and adipose tissues, playing a pivotal role in maintaining lipid and glucose homeostasis. LSR binds to lipoproteins in the presence of free fatty acids, facilitating the uptake and clearance of lipids from the bloodstream, which is significant in preventing atherosclerosis and other lipid-related disorders. The protein functions as a multi-subunit complex, which includes two isoforms, LSRα and LSRβ, each contributing to lipoprotein metabolism. Research has highlighted its involvement in metabolic processes and its potential impacts on obesity and insulin resistance. LSR has also been studied in the context of hepatic lipid accumulation, where its downregulation is associated with increased lipid deposition in the liver, suggesting its importance in preventing non-alcoholic fatty liver disease (NAFLD). Due to its central role in lipid metabolism, LSR has emerged as a potential therapeutic target for metabolic diseases and cardiovascular conditions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LSR
Applications Immunohistochemistry (Paraffin), Western Blot, Western Blot
Classification Monoclonal
Clone C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene LSR
Gene Accession No. Q86X29, Q9WU74
Gene Alias ILDR3; immunoglobulin-like domain containing receptor 3; lipolysis stimulated lipoprotein receptor; lipolysis stimulated receptor; lipolysis-stimulated lipoprotein receptor; Lipolysis-stimulated receptor; lipolysis-stimulated remnant; lipolysis-stimulated remnant receptor; LISCH; LISCH protein; LISCH7; Liver-specific bHLH-Zip transcription factor; liver-specific bHLH-Zip transcription factor 7; liver-specific gene on mouse chromosome 7 protein; LSR
Gene Symbols LSR
Host Species Mouse
Immunogen Recombinant protein Lipolysis Stimulated Lipoprotein Receptor. The antigen corresponds to amino acid range 335-589 of the target protein.
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51599, 64355
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.