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  5. Tocris Bioscience™ LY 294002 hydrochloride

Tocris Bioscience™ LY 294002 hydrochloride
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Catalog No. 11305
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

LY 294002 hydrochloride is a prototypical PI 3-kinase inhibitor (IC50 values are 0.31, 0.73, 1.06 and 6.60 μM for PI 3-Kβ, PI 3-Kα, PI 3-Kδ and PI 3-Kγ respectively). Also inhibits other kinases including, CK2, mTOR, PLK1, PIM1 and PIM3. Inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo. Suppresses proliferation of mESCs. Inhibits autophagic sequestration in rat hepatocytes.

Negative Control also available.

Chemical Identifiers

CAS 934389-88-5
Molecular Formula C19H18ClNO3

Specifications

Quantity 5 mg
Formula Weight 343.81
Purity >99%
Molecular Weight (g/mol) 343.807
Chemical Name or Material LY 294002 hydrochloride

Safety and Handling

Recommended Storage Store at Room Temperature
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