Ly-6G and Ly-6C Rat anti-Mouse, Unlabeled, Clone: RB6-8C5, BD

Rat Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB553123	BD Biosciences 553123	0.5 mg
BDB550291	BD Biosciences 550291	1 mL
BDB557445	BD Biosciences 557445	0.1 mg

Description

The RB6-8C5 antibody reacts with a common epitope on Ly-6G and Ly-6C, previously known as the myeloid differentiation antigen Gr-1. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. The antigen is also expressed on the monocyte lineage in the bone marrow, but not on erythroid cells. In the periphery, RB6-8C5 antibody recognizes granulocytes (neutrophils and eosinophils) and monocytes. The RB6-8C5 mAb is a component of the “lineage cocktail” used in studies of hematopoietic lineages. The mAb 1A8 (Cat. No. 551461) specifically recognizes Ly-6G, but not Ly-6C. This antibody is routinely tested by immunohistochemistry. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Rat
Clone: RB6-8C5
Isotype: IgG2b κ
Species Reactivity: Mouse

Immunohistochemistry, Immunohistochemistry (Frozen)

Specifications

• Antigen: Ly-6G and Ly-6C
• Concentration: 0.5mg/mL
• Classification: Monoclonal
• Host Species: Rat
• Research Discipline: Immunology
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Isotype: IgG2b κ
• Purification Method: Affinity Purified
• Description: Ly6c, Lymphocyte antigen 6C2; Lymphocyte antigen 6G, Ly6g, Gr-1

• Clone: RB6-8C5
• Applications: Flow Cytometry
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Target Species: Mouse
• Immunogen: Not Reported
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

For Research Use Only.