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Lymphotoxin beta Receptor Monoclonal Antibody (eBio3C8 (3C8)), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
$3081.65
Specifications
| Antigen | Lymphotoxin beta Receptor |
|---|---|
| Clone | eBio3C8 (3C8) |
| Concentration | 1 mg/mL |
| Applications | Flow Cytometry, Functional Assay |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
16-567-138
|
Invitrogen™
16567138 |
5 mg |
Each of 1
for $3,081.65
Save 8% Reg : |
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Description
The antibody reacts with mouse lymphotoxin-beta receptor (LTBR). Northern blot analysis of tissues from adult mice showed that expression levels of LTBR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. The tumor necrosis factor receptor-related protein is the human receptor for the heterotrimer of lymphotoxinalpha and lymphotoxin beta. This LT alpha/LTbeta heterotrimer (LT alpha 1/beta 2) is assumed to take part in immunologic reactions by cell-cell contact, but does not bind to either TNFR1 (CD120 alpha) or TNFR2 (CD120 beta). LTBR is expressed by day 7 embryos, so it has been speculated that the LT alpha/LT beta receptor system may also have some function in early embryogenesis.
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.Specifications
| Lymphotoxin beta Receptor | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with no preservative; pH 7.2 | |
| 17000 | |
| Primary | |
| 4°C | |
| Ltbr |
| eBio3C8 (3C8) | |
| Flow Cytometry, Functional Assay | |
| Functional Grade | |
| Rat | |
| Mouse | |
| P50284 | |
| IgG1 κ | |
| Affinity chromatography | |
| Antibody |
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