Invitrogen™ MAFA Recombinant Rabbit Monoclonal Antibody (BLR067G)

Rabbit Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA544325	Invitrogen™ MA544325	100 μL
PIMA544326	Invitrogen™ MA544326	10 μL

Description

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its ocogenic activity. Serves as an ocogene or tumor supressor depending on the cell context.

Specifications

• Antigen: MAFA
• Concentration: 1 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: BBS with 0.09% sodium azide; pH 8.2
• Gene Accession No.: Q8NHW3
• Gene ID (Entrez): 389692
• Immunogen: Peptide representing a region between residue 125 and 175 of human MAF bZIP transcription factor A.
• Product Type: Antibody

• Clone: BLR067G
• Content And Storage: 4°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: Mafa
• Gene Alias: hMafA; MAF bZIP transcription factor A; MAFA; Mafa homolog; pancreatic beta-cell-specific transcriptional activator; RGD1562627; RIPE3b1; RIPE3b1 factor; Transcription factor MafA; transcription factor RIPE3b1; v-maf avian musculoaponeurotic fibrosarcoma oncogene A; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog A
• Gene Symbols: Mafa
• Primary or Secondary: Primary
• Purification Method: purified