Invitrogen™ MARCKSL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA548796

Catalog No. PA548796

Description

Predicted to react with bovine, mouse, rabbit and rat based on sequence homology.

MARCKS (Myristoylated alanine-rich protein kinase C substrate), also designated 80K or 80K-L, is a 332 amino acid protein that localizes to the plasma membrane and functions as a major cellular substrate for protein kinase C (PKC). MARCKSL1 (MARCKS-like protein 1), also known as MacMARCKS, MLP, MRP, or F52, is a 195 amino acid protein that, like MARCKS, is a major substrate for PKC. Expressed in a variety of tissues with highest levels found in testis and uterus, MARCKSL1 participates in the coordination of membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis and cell adhesion. Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading.

Specifications

• Antigen: MARCKSL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Marcksl1
• Gene Alias: AL022768; AW215397; AW536807; brain protein F52; D4Bc1; F52; MACMARCKS; Mac-MARCKS; Macrophage myristoylated alanine-rich C kinase substrate; Macs2; Macs3; MARCKS like 1; Marcksl1; MARCKS-like 1; MARCKS-like protein 1; MARCKS-related protein; MLP; MLP1; Mrp; myristoylated alanine-rich C kinase substrate
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 65108
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P49006
• Gene Symbols: Marcksl1
• Immunogen: KLH conjugated synthetic peptide between 132-160 amino acids from the C-terminal region of human MARCKSL1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG