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MARCO Monoclonal Antibody (PLK-1), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

$199.00 - $426.00

Specifications

Antigen MARCO
Clone PLK-1
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
17-544-741
Encompass_Preferred
View Documents
Invitrogen™
17544741
25 Tests
Each for $199.00
Only null left
Add to Cart
 
17-544-742
Encompass_Preferred
View Documents
Invitrogen™
17544742
100 Tests
Each for $426.00
Only null left
Edge
Add to Cart
 
Description

Description

Description: This PLK-1 monoclonal antibody recognizes human MARCO also known as SR-A6 or SCARA2. Applications Reported: This PLK-1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This PLK-1 antibody has been pre-diluted and tested by flow cytometric analysis of human monocyte-derived macrophages. This may be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser

MARCO, also known as SR-A6 or SCARA2, is a macrophage surface receptor and a member of the class A scavenger receptor family. As a part of the innate antimicrobial immune system, MARCO can bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. Due to its expression in tumor infiltrating macrophages, and its role in inhibiting immune responses within tumor environment, MARCO has been indicated as a potential target for cancer immunotherapy.
Specifications

Specifications

MARCO
5 μL/Test
Monoclonal
Liquid
RUO
PBS with BSA and 0.09% sodium azide; pH 7.2
AI323439; Ly112; macrophage receptor MARCO; Macrophage receptor with collagenous structure; MARCO; SCARA2; Scavenger receptor class A member 2; scavenger receptor class A, member 2; SR-A6
Marco
IgG3
Affinity chromatography
Antibody
PLK-1
Flow Cytometry
APC
Mouse
Human
Q9UEW3
8685
Human alveolar macrophages.
Primary
4°C, store in dark, DO NOT FREEZE!
Marco
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