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MCM4 Polyclonal Antibody, Bethyl Laboratories

Goat Polyclonal Antibody

$151.31

Specifications

Antigen MCM4
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Form Liquid
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-155-6947
Encompass_Preferred
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Bethyl Laboratories, Inc
A300125AT
20 μL
Each of 1 for $151.31
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Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
Specifications

Specifications

MCM4
Polyclonal
Liquid
RUO
TBS with 0.1% BSA and 0.09% sodium azide
CDC21, CDC54, P1-CDC21, hCdc21, CDC21 homolog, DNA replication licensing factor MCM4, MCM4 minichromosome maintece deficient 4, homolog of S. pombe cell devision cycle 21, minichromosome maintece deficient 4
Between 325 and 375
Primary
4° C
MCM4
Immunohistochemistry, Western Blot
Unconjugated
Goat
Human, Mouse
P33991, P49717
17217, 4173
IgG
Antigen affinity chromatography
Antibody
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