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MCM6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501728670 Shop All Proteintech Group Inc Products
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50-172-8670 150 μL
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Catalog No. 50-172-8670 Supplier Proteintech Group Inc Supplier No. 133472AP150UL
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Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

Specifications

Antigen MCM6
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MCM6
Gene Accession No. P97311, Q14566, Q62724
Gene Alias MCG40308, MCM6, Mis5, P105MCM
Gene Symbols Mcm6
Host Species Rabbit
Immunogen MCM6 Fusion Protein Ag4180
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17219, 29685, 4175
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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