MCM6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8670	Proteintech Group Inc 133472AP150UL	150 μL

Description

The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

Specifications

• Antigen: MCM6
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P97311, Q14566, Q62724
• Gene ID (Entrez): 17219, 29685, 4175
• Immunogen: MCM6 Fusion Protein Ag4180
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: MCM6

• Concentration: 0.13 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: MCG40308, MCM6, Mis5, P105MCM
• Gene Symbols: Mcm6
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody