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MCM7 Mouse anti-Human, Clone: MCM7/1467, Novus Biologicals™
SDP

Catalog No. NBP25960820 Shop All R&D Systems Products
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Catalog No. NBP25960820 Supplier Novus Biologicals Supplier No. NBP25960820UG
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Mouse Monoclonal Antibody

MCM7 Monoclonal specifically detects MCM7 in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array.

Specifications

Antigen MCM7
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page
Classification Monoclonal
Clone MCM7/1467
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, SDS-Page, Protein Array 1:100-1:2000
Formulation 0mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Alias CDC47 homolog, CDC47P85MCM, DNA replication licensing factor MCM7, EC 3.6.4.12, homolog of S. cerevisiae Cdc47, MCM2PNAS146, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae), minichromosome maintenance complex component 7, minichromosome maintenance deficient (S. cerevisiae) 7, minichromosome maintenance deficient 7, P1.1-MCM3, P1CDC47
Gene Symbols MCM7
Host Species Mouse
Immunogen Recombinant human MCM7 protein fragment (aa195-319) (exact sequence is proprietary)
Molecular Weight of Antigen 88 kDa
Purification Method Protein A or G purified
Quantity 20 μg
Regulatory Status RUO
Research Discipline Cell Cycle and Replication, Cellular Markers, Core ESC Like Genes, DNA Repair, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 4176
Test Specificity The specificity of this monoclonal antibody to its intended target was validated by HuProt Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by theMCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG2a κ
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