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Invitrogen™ MCP-4 Monoclonal Antibody (3G4)
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Catalog No. PIM809
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200 μg
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Catalog No. Quantity
PIM809 200 μg
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Catalog No. PIM809 Supplier Invitrogen™ Supplier No. M809
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Description

Mouse Monoclonal Antibody

There is one major form (long chain) and two minor forms (short chain and medium chain) of MCP-4 produced by differential signal peptide cleavage. Thus, the resulting MW of secreted MCP-4 ranges between ~8-9kD. Western blot analysis of recombinant MCP-4/CCL13 protein detects an ~17kD band, likely corresponding to a dimer of MCP-4. The M809 MCP-4 antibody (clone 3G4) has successfully been paired as the coating antibody in a sandwich ELISA with detection antibody M810 (biotinylated conjugate of clone 8C12). The M809 MCP-4 antibody (biotinylated conjugate of clone 3G4) has also been used successfully in a sandwich ELISA as a detection antibody when paired with M810 (clone 8C12) as the coating antibody.

Monocyte Chemotactic Protein 4 (MCP-4), also called CCL13, is induced by inflammatory proteins such as IL-1 and TNFalpha. MCP-4 is a ligand for three different G protein coupled receptors, CCR2, CCR3 and CCR5. MCP-4 activates signaling in monocytes, T lymphocytes, eosinophils and basophils and this signaling is associated with the allergic response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCP-4
Applications ELISA, Western Blot
Classification Monoclonal
Clone 3G4
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CCL13
Gene Accession No. Q99616
Gene Alias C-C motif chemokine 13; C-C motif chemokine 13, long chain; C-C motif chemokine 13, medium chain; C-C motif chemokine 13, short chain; C-C motif chemokine ligand 13; CCL 13; CCL13; chemokine (C-C motif) ligand 13; CKb10; CK-beta-10; H-MCP-4; MCP4; MCP-4; Monocyte chemoattractant protein 4; monocyte chemotactic protein 4; NCC1; NCC-1; new CC chemokine 1; SCYA13; SCYL1; small inducible cytokine subfamily A (Cys-Cys), member 13; small-inducible cytokine A13
Gene Symbols CCL13
Host Species Mouse
Immunogen Recombinant CCL13 protein.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6357
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

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