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MDC1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7139955
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50-155-6807 20 μL
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Catalog No. 50-155-6807 Supplier Bethyl Laboratories, Inc Supplier No. A300053AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predict

The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.

Specifications

Antigen MDC1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene MDC1
Gene Accession No. Q14676
Gene Alias DAAP-285E11.7, DKFZp781A0122, KIAA0170, MGC166888, NFBD1
Gene Symbols MDC1
Host Species Rabbit
Immunogen Between 1375 and 1425
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9656
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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