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Melan-A/MART-1 Antibody (SPM342), HRP, Novus Biologicals™
SDP

Catalog No. NBP234765H Shop All R&D Systems Products
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NBP234765H 0.1 mL
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Catalog No. NBP234765H Supplier Novus Biologicals Supplier No. NBP234765H
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Description

Mouse Monoclonal Antibody

Melan-A/MART-1 Monoclonal specifically detects Melan-A/MART-1 in Human, Equine, Mouse (Negative), Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Melan-A/MART-1
Applications Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), Immunoprecipitation
Classification Monoclonal
Clone SPM342
Conjugate HRP
Dilution Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias Antigen LB39-AA, Antigen SK29-AA, Mart 1 Melan A, MART1MART-1, melan-A, melanoma antigen recognized by T-cells 1, Protein Melan-A
Gene Symbols MLANA
Host Species Mouse
Immunogen Recombinant Melan-A/MART-1 protein (Uniprot: Q16655)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cytoskeleton Markers, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 2315
Test Specificity This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This monoclonal antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Target Species Human, Equine, Mouse (Negative), Rat (Negative)
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG2b λ
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For Research Use Only

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