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Melanoma Associated Antigen (KBA.62) Antibody (KBA.62), Novus Biologicals™
SDP

Catalog No. NBP24528500 Shop All R&D Systems Products
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NBP24528500 0.02 mg
NBP24528501 0.1 mg
NBP24528502 0.2 mg
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Catalog No. NBP24528500 Supplier Novus Biologicals Supplier No. NBP2452850.02MG
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Immunohistochemistry (Paraffin), Immunofluorescence

Melanoma Associated Antigen (KBA.62) Monoclonal specifically detects Melanoma Associated Antigen (KBA.62) in Human samples. It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen Melanoma Associated Antigen (KBA.62)
Applications Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Classification Monoclonal
Clone KBA.62
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Host Species Mouse
Immunogen Human KAL cells derived from lymph node metastasis of malignant melanoma
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity KBA.62 is a novel anti-melanoma antibody. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, it reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes. KBA.62 antibody is useful in identifying malignant melanomas. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, sarcomas, spindle cell carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immuno-reacts with antibody to S-100 protein and with KBA.62 antibody is, with rare exception, a melanoma. Anti-KBA.62 is a useful additional marker for melanoma, specifically in desmoplastic/spindle cell cases and in the context of micro-metastasis in sentinel lymph node.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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