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Melanoma Marker (MART-1 + Tyrosinase + gp100) Antibody (M2-7C10 + M2-9E3 + T311 + HMB45), DyLight 680, Novus Biologicals™
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Catalog No. NBP234681FR Shop All R&D Systems Products
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Catalog No. NBP234681FR Supplier Novus Biologicals Supplier No. NBP234681FR
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Description

Mouse Monoclonal Antibody

Melanoma Marker (MART-1 + Tyrosinase + gp100) Monoclonal specifically detects Melanoma Marker (MART-1 + Tyrosinase + gp100) in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

Antigen Melanoma Marker (MART-1 + Tyrosinase + gp100)
Applications Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone M2-7C10 + M2-9E3 + T311 + HMB45
Conjugate DyLight 680
Dilution Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias MART1, MART-1, melan-A, MLANA
Host Species Mouse
Immunogen Recombinant hMART-1 protein (M2-7C10; M2-9E3); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2315
Test Specificity This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Target Species Human
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG2b λ, IgG2a κ, IgG1 κ
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