MHC Class I Antibody (MEM-E/06), Alexa Fluor™ 405, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NB500307AF405

Catalog No. NB500307W

Description

MHC Class I Monoclonal specifically detects MHC Class I in Human, Primate samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: MHC Class I
• Classification: Monoclonal
• Conjugate: Alexa Fluor 405
• Gene Alias: DKFZp686P19218, EA1.2, EA2.1, HLA class I histocompatibility antigen, alpha chain E, HLA class I histocompatibility antigen, E alpha chain, HLA-6.2, HLAE, lymphocyte antigen, major histocompatibility complex, class I, E, MHC, MHC class I antigen E, MHC HLA-E alpha-1, MHC HLA-E alpha-2.1, QA1
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This antibody (clone MEM-E/06) recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. Some resultss showed that this antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, others have confirmed that this antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.
• Content And Storage: Store at 4C in the dark.

• Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
• Clone: MEM-E/06
• Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
• Gene Symbols: HLA-E
• Immunogen: Bacterially expressed recombinant full length protein refolded with beta2-microglobulin and peptide (Human).
• Quantity: 0.1 mL
• Research Discipline: Adaptive Immunity, Immunology, Major Histocompatibility Complexes
• Gene ID (Entrez): 3133
• Target Species: Human, Primate
• Isotype: IgG1

For Research Use Only