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MHC Class I Antibody (MEM-E/06), DyLight 488, Novus Biologicals™
SDP

Catalog No. NB500307G Shop All R&D Systems Products
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NB500307G 0.1 mL
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Catalog No. NB500307G Supplier Novus Biologicals Supplier No. NB500307G
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Mouse Monoclonal Antibody

MHC Class I Monoclonal specifically detects MHC Class I in Human, Primate samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen MHC Class I
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone MEM-E/06
Conjugate DyLight 488
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias DKFZp686P19218, EA1.2, EA2.1, HLA class I histocompatibility antigen, alpha chain E, HLA class I histocompatibility antigen, E alpha chain, HLA-6.2, HLAE, lymphocyte antigen, major histocompatibility complex, class I, E, MHC, MHC class I antigen E, MHC HLA-E alpha-1, MHC HLA-E alpha-2.1, QA1
Gene Symbols HLA-E
Host Species Mouse
Immunogen Bacterially expressed recombinant full length protein refolded with beta2-microglobulin and peptide (Human).
Purification Method Affinity Purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Adaptive Immunity, Immunology, Major Histocompatibility Complexes
Primary or Secondary Primary
Gene ID (Entrez) 3133
Test Specificity This antibody (clone MEM-E/06) recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. Some resultss showed that this antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, others have confirmed that this antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.
Target Species Human, Primate
Content And Storage Store at 4C in the dark.
Isotype IgG1
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For Research Use Only

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