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MHC Class I Antibody (MEM-E/06), DyLight 650, Novus Biologicals™
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Catalog No. NB500307C Shop All R&D Systems Products
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NB500307C 0.1 mL
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Catalog No. NB500307C Supplier Novus Biologicals Supplier No. NB500307C
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Description

Mouse Monoclonal Antibody

MHC Class I Monoclonal specifically detects MHC Class I in Human, Primate samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen MHC Class I
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone MEM-E/06
Conjugate DyLight 650
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias DKFZp686P19218, EA1.2, EA2.1, HLA class I histocompatibility antigen, alpha chain E, HLA class I histocompatibility antigen, E alpha chain, HLA-6.2, HLAE, lymphocyte antigen, major histocompatibility complex, class I, E, MHC, MHC class I antigen E, MHC HLA-E alpha-1, MHC HLA-E alpha-2.1, QA1
Gene Symbols HLA-E
Host Species Mouse
Immunogen Bacterially expressed recombinant full length protein refolded with beta2-microglobulin and peptide (Human).
Purification Method Protein A purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, Asthma, Cell Biology, Core ESC Like Genes, Diabetes Research, DNA Repair, DNA replication Transcription Translation and Splicing, Immunology, Major Histocompatibility Complexes, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 3133.0
Test Specificity This antibody (clone MEM-E/06) recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. Some resultss showed that this antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, others have confirmed that this antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.
Target Species Human, Primate
Content And Storage Store at 4°C in the dark.
Isotype IgG1
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