MHC Class I Antibody (MEM-E/08), DyLight 350, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NB500305UV

Catalog No. NB500305UV

Description

MHC Class I Monoclonal specifically detects MHC Class I in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: MHC Class I
• Classification: Monoclonal
• Conjugate: DyLight 350
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: HLA-E
• Immunogen: Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide.
• Quantity: 0.1 mL
• Research Discipline: Adaptive Immunity, Asthma, Cell Biology, Diabetes Research, Immunology, Major Histocompatibility Complexes
• Gene ID (Entrez): 3133
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry
• Clone: MEM-E/08
• Dilution: Flow Cytometry
• Gene Alias: DKFZp686P19218, EA1.2, EA2.1, HLA class I histocompatibility antigen, alpha chain E, HLA class I histocompatibility antigen, E alpha chain, HLA-6.2, HLAE, lymphocyte antigen, major histocompatibility complex, class I, E, MHC, MHC class I antigen E, MHC HLA-E alpha-1, MHC HLA-E alpha-2.1, QA1
• Host Species: Mouse
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This antibody (clone MEM-E/08) recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The results revealed that antibody is remarkably specific for HLA-E, only with weak cross-reactivity with following classical MHC Class I molecules (MHC Class Ia): HLA-A24, -B7, -B27, -B51, -B54, -C7.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1