MHC class II (I-A/I-E) Antibody (M5/114.15.2), Janelia Fluor™ 646, Novus Biologicals™

Rat Monoclonal Antibody

Supplier:  Novus Biologicals NBP143312JF646

Catalog No. NBP43312646

Description

MHC class II (I-A/I-E) Monoclonal specifically detects MHC class II (I-A/I-E) in Human, Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

• Antigen: MHC class II (I-A/I-E)
• Classification: Monoclonal
• Conjugate: Janelia Fluor 646
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: H2-Ea-ps
• Immunogen: The immunogen for this antibody was MHC Class II.
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG2b κ

• Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
• Clone: M5/114.15.2
• Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Alias: class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM
• Host Species: Rat
• Purification Method: Protein A or G purified
• Research Discipline: Adaptive Immunity, Asthma, B Cell Development and Differentiation Markers, Cell Biology, Diabetes Research, Immune System Diseases, Immunology, Major Histocompatibility Complexes, Transcription Factors and Regulators
• Gene ID (Entrez): 100504404
• Target Species: Human, Mouse
• Form: Purified