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MHC Class II RT1Bu Antibody (OX-3), Alexa Fluor™ 647, Novus Biologicals™
SDP

Catalog No. NB10065011Y Shop All R&D Systems Products
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0.25 mL
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NB10065011Y 0.25 mL
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Catalog No. NB10065011Y Supplier Novus Biologicals Supplier No. NB10065011AF647
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Mouse Monoclonal Antibody

MHC Class II RT1Bu Monoclonal specifically detects MHC Class II RT1Bu in Rat samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin).

Specifications

Antigen MHC Class II RT1Bu
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone OX-3
Conjugate Alexa Fluor 647
Dilution Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias Clone P2-beta-3, DR1, DR-1, DR12, DR-12, DR13, DR-13, DR14, DR-14, DR16, DR-16, DR4, DR-4, DR5, DR-5, DR7, DR-7, DR8, DR-8, DR9, DR-9, DRB1, DRw10, DRw11, DRw8, DW2.2/DR2.2, FLJ75017, FLJ76359, HLA class II antigen beta chain, HLA class II histocompatibility antigen, DR-1 beta chain, HLA-DR1B, HLA-DRB, HLA-DRB1*, HLA-DRB2, HLA-DR-beta 1, human leucocyte antigen DRB1, leucocyte antigen DR beta 1 chain, leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex, class II, DR beta 1, MHC class II antigen DRB1*1, MHC class II antigen DRB1*10, MHC class II antigen DRB1*11, MHC class II antigen DRB1*12, MHC class II antigen DRB1*13, MHC class II antigen DRB1*14, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II antigen DRB1*4, MHC class II antigen DRB1*7, MHC class II antigen DRB1*8, MHC class II antigen DRB1*9, MHC class II antigen HLA-DR13, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface gly
Gene Symbols HLA-DRB1
Host Species Mouse
Immunogen Rat thymocyte membrane glycoproteins
Purification Method Affinity Purified
Quantity 0.25 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3123
Test Specificity NB100-65011 recognizes a polymorphic determinant of rat Ia antigen (RT1Bu) present on Lewis, Wistar and AO strain rats but not BN, DA or PVG/c strains (1,2). This antibody is useful for distinguishing Ia positive cells from different rat strains, e.g. for recognizing cells of donor origin in bone marrow reconstituted radiation chimaeras (3,4). MRC OX-3 cross reacts with mouse strains of MHC haplotypes b and s, and analysis of recombinant mouse strains showed that the determinants mapped to the I-A region. NB100-65011 recognizes Ia antigens on B-cells, dendritic cells and certain epithelial cells (1,3,4). This product is routinely tested in flow cytometry on Lewis rat splenocytes.
Target Species Rat
Content And Storage Store at 4C in the dark.
Isotype IgG1
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