MHC Class II RT1Bu Antibody (OX-3), DyLight 488, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NB10065011G

Catalog No. NB10065011G

Description

MHC Class II RT1Bu Monoclonal specifically detects MHC Class II RT1Bu in Mouse, Rat samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

• Antigen: MHC Class II RT1Bu
• Classification: Monoclonal
• Conjugate: DyLight 488
• Gene Alias: Clone P2-beta-3, DR1, DR-1, DR12, DR-12, DR13, DR-13, DR14, DR-14, DR16, DR-16, DR4, DR-4, DR5, DR-5, DR7, DR-7, DR8, DR-8, DR9, DR-9, DRB1, DRw10, DRw11, DRw8, DW2.2/DR2.2, FLJ75017, FLJ76359, HLA class II antigen beta chain, HLA class II histocompatibility antigen, DR-1 beta chain, HLA-DR1B, HLA-DRB, HLA-DRB1*, HLA-DRB2, HLA-DR-beta 1, human leucocyte antigen DRB1, leucocyte antigen DR beta 1 chain, leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex, class II, DR beta 1, MHC class II antigen DRB1*1, MHC class II antigen DRB1*10, MHC class II antigen DRB1*11, MHC class II antigen DRB1*12, MHC class II antigen DRB1*13, MHC class II antigen DRB1*14, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II antigen DRB1*4, MHC class II antigen DRB1*7, MHC class II antigen DRB1*8, MHC class II antigen DRB1*9, MHC class II antigen HLA-DR13, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface gly
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 3123
• Target Species: Mouse, Rat
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: OX-3
• Dilution: Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Symbols: HLA-DRB1
• Immunogen: Rat thymocyte membrane glycoproteins
• Quantity: 0.25 mL
• Primary or Secondary: Primary
• Test Specificity: NB100-65011 recognizes a polymorphic determinant of rat Ia antigen (RT1Bu) present on Lewis, Wistar and AO strain rats but not BN, DA or PVG/c strains (1,2). This antibody is useful for distinguishing Ia positive cells from different rat strains, e.g. for recognizing cells of donor origin in bone marrow reconstituted radiation chimaeras (3,4). MRC OX-3 cross reacts with mouse strains of MHC haplotypes b and s, and analysis of recombinant mouse strains showed that the determinants mapped to the I-A region. NB100-65011 recognizes Ia antigens on B-cells, dendritic cells and certain epithelial cells (1,3,4). This product is routinely tested in flow cytometry on Lewis rat splenocytes.
• Content And Storage: Store at 4C in the dark.

For Research Use Only