Invitrogen™ MIF Recombinant Rabbit Monoclonal Antibody (BLR141J)

Rabbit Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA544469	Invitrogen™ MA544469	100 μL
PIMA544470	Invitrogen™ MA544470	10 μL

Description

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

MIF (macrophage migration inhibitory factor) was one of the first cytokine activities to be discovered and was initially described as a T cell-derived factor that inhibits the random migration of macrophages (Weiser 1989). Recently, MIF was rediscovered as a pituitary hormone that act as the counterregulatory hormone for glucocorticoid action within the immune system (Bernhagen 1993, Mitchell 1995). MIF was released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secreted MIF counter-regulates the immunosuppressive effects of steroids on immune cell activation and cytokine production (Bucala 1998). MIF plays a critical role in the host control of inflammation and immunity.

Specifications

• Antigen: MIF
• Concentration: 50 μg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 6.8-7.4
• Gene Accession No.: P14174
• Gene ID (Entrez): 4282
• Immunogen: Recombinant protein representing Human Macrophage migration inhibitory factor (residues 2-115).
• Product Type: Antibody

• Clone: BLR141J
• Content And Storage: 4°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: Mif
• Gene Alias: cytokine; delayed early response protein 6; DER6; GIF; GLIF; glutathione-binding 13 kDa protein; Glycosylation-inhibiting factor; HGNC:7097; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor; macrophage migration inhibitory factor (glycosylation-inhibiting factor); MGC107654; Mif; MMIF; phenylpyruvate tautomerase
• Gene Symbols: Mif
• Primary or Secondary: Primary
• Purification Method: purified