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  5. Tocris Bioscience™ Mirtazapine

Tocris Bioscience™ Mirtazapine
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Catalog No. 201810
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20-181-0 10 mg
20-185-0 50 mg
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Catalog No. 20-181-0 Supplier Tocris Bioscience™ Supplier No. 2018/10
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Description

Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

Mirtazapine is an antidepressant agent; potent 5-HT2, 5-HT3 and histamine H1 receptor antagonist and moderately potent α2-adrenoceptor antagonist (pKi values are 8.05, ∼ 8.1, 9.3 and 6.95 respectively). Enhances noradrenaline (NA) release in rat brain via inhibition of α2-adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pKi values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo.

Chemical Identifiers

CAS 85650-52-8
Molecular Formula C17H19N3

Specifications

Quantity 10 mg
Formula Weight 265.36
Purity >99%
Molecular Weight (g/mol) 265.36
Chemical Name or Material Mirtazapine

Safety and Handling

Recommended Storage Store at Room Temperature
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