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  10. ML 218 hydrochloride, Tocris Bioscience™ 

ML 218 hydrochloride, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
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2319922-08-0
C19H27Cl3N2O
405.788
IDCVEUISZZKMKJ-ZXVFAPHLSA-N
ml 218 hydrochloride,3,5-dichloro-n-1?,5?,6-exo,6?-3-3,3-dimethylbutyl-3-azabicyclo 3.1.0 hex-6-yl methyl-benzamide hydrochloride
90488946
3,5-dichloro-N-[[(1S,5R)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide;hydrochloride
CC(C)(C)CCN1CC2C(C1)C2CNC(=O)C3=CC(=CC(=C3)Cl)Cl.Cl
This item is not returnable. View return policy
2319922-08-0
C19H27Cl3N2O
405.788
IDCVEUISZZKMKJ-ZXVFAPHLSA-N
ml 218 hydrochloride,3,5-dichloro-n-1?,5?,6-exo,6?-3-3,3-dimethylbutyl-3-azabicyclo 3.1.0 hex-6-yl methyl-benzamide hydrochloride
90488946
3,5-dichloro-N-[[(1S,5R)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide;hydrochloride
CC(C)(C)CCN1CC2C(C1)C2CNC(=O)C3=CC(=CC(=C3)Cl)Cl.Cl

Description

CaV3.x blocker

Selective inhibitor of T-type calcium channels (IC50 values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Decreases burst activity in STN neurons; reduces cataleptic behaviour in an in vivo rat model of Parkinson's disease. Displays no significant inhibition of L- or N-type calcium channels, Kir6 (KATP) or KV11.1 (hERG) potassium channels. Orally active.

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Quantity 10mg
Formula Weight 405.79
Percent Purity >99%
Chemical Name or Material ML 218 hydrochloride

Safety and Handling

Recommended Storage : Store at +4°C