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Tocris Bioscience™ ML 218 hydrochloride
GREENER_CHOICE

Catalog No. 450710
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

CaV3.x blocker

ML 218 hydrochloride is a selective inhibitor of T-type calcium channels (IC50 values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Decreases burst activity in STN neurons; reduces cataleptic behaviour in an in vivo rat model of Parkinson's disease. Displays no significant inhibition of L- or N-type calcium channels, Kir6 (KATP) or KV11.1 (hERG) potassium channels. ML 218 hydrochloride inhibits oral cancer cell proliferation. Orally active.

Chemical Identifiers

CAS 2319922-08-0
Molecular Formula C19H27Cl3N2O

Specifications

Quantity 10 mg
Formula Weight 405.79
Purity >99%
Molecular Weight (g/mol) 405.788
Chemical Name or Material ML 218 hydrochloride
Recommended Storage Store at +4°C
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