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Tocris Bioscience™ ML 240
ATP-competitive inhibitor of p97 ATPase
Supplier: Tocris Bioscience™ 5153/50
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Description
ML 240 is an ATP-competitive inhibitor of p97 ATPase (VCP, IC50 = 110 nM). Exhibits antiproliferative activity in NCI-60 cancer cell lines and rapidly induces executioner caspases 3 and 7 in multiple colon cancer cells. Promotes accumulation of LC3-II and impairs autophagosome maturation. Also impairs the endoplasmic-reticulum-associated degradation (ERAD) pathway.Specifications
>99% | |
ML 240 | |
ML 240 |
50 mg | |
396.44 |
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