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MLF1 Monoclonal Antibody (OTI2D6), TrueMAB™, OriGene
SDP

Catalog No. 501675383
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50-167-5383 100 μL
50-254-0129 30 μL
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Catalog No. 50-167-5383 Supplier OriGene Supplier No. TA504765
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Description

Mouse Monoclonal Antibody

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Specifications

Antigen MLF1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI2D6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene MLF1
Gene Accession No. P58340
Gene Alias myeloid leukemia factor 1
Gene Symbols MLF1
Host Species Mouse
Immunogen Full length human recombit protein of human MLF1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4291
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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