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MLF1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501557902
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Catalog No. Quantity
50-155-7902 20 μL
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Catalog No. 50-155-7902 Supplier Bethyl Laboratories, Inc Supplier No. A300552AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Specifications

Antigen MLF1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene MLF1
Gene Accession No. P58340
Gene Alias Myeloid leukemia factor 1; Myelodysplasia-myeloid leukemia factor 1; MLF1
Gene Symbols MLF1
Host Species Rabbit
Immunogen Between 200 and C-term
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4291
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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