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Invitrogen™ MLK1 Polyclonal Antibody
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Catalog No. PIPA529827
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100 μL
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Catalog No. Quantity
PIPA529827 100 μL
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Catalog No. PIPA529827 Supplier Invitrogen™ Supplier No. PA529827
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4, Raji, Jurkat, Raji, NCI-H929. Predicted reactivity: Mouse (99%), Rat (97%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MAP3K9 (MLK1) is a serine/threonine protein kinase that functions in the MAP kinase pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MLK1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene MAP3K9
Gene Accession No. P80192
Gene Alias E130314H24Rik; Map3k9; MEKK9; mitogen activated protein kinase kinase kinase 9; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); mixed-lineage kinase 1; MLK1; Prke1; RGD1562149
Gene Symbols MAP3K9
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MLK1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4293
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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