Invitrogen™ MMP13 Monoclonal Antibody (C2)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA541638	Invitrogen™ MA541638	200 μL
PIMA543722	Invitrogen™ MA543722	20 μL

Description

MMP13 Monoclonal Antibody for Western Blot

MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.

Specifications

• Antigen: MMP13
• Concentration: 1 mg/mL
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P45452
• Gene ID (Entrez): 4322
• Immunogen: Recombinant protein Matrix Metalloproteinase 13. The antigen corresponds to amino acid range 103-290 of the target protein.
• Product Type: Antibody

• Clone: C2
• Content And Storage: -20°C
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG1 κ
• Target Species: Human
• Gene: MMP13
• Gene Alias: cb1034; Clg; CLG3; Collagenase; collagenase 3; collagenase 3a; matrix metalloproteinase 13a; collagenase-1; Collagenase3; Collagenase-3; collagenase-3 precursor; interstitial collagenase; MANDP1; matrix metallo protease; matrix metallopeptidase 13; matrix metallopeptidase 13 (collagenase 3); matrix metallopeptidase 13a; matrix metallopeptidase 13a (collagenase 3); matrix metalloproteinase 13; matrix metalloproteinase 13 (collagenase 3); matrix metalloproteinase-13; matrix metalloproteinase-13; MMP-13; interstitial protein; MMP; Mmp1; MMP13; MMP-13; mmp13 protein; mmp13a; MMPLg; MMPLh; MMPs; Procollagenase 3; UMRCASE; ZFMMP13
• Gene Symbols: MMP13
• Primary or Secondary: Primary
• Purification Method: Protein A/G