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  6. MMP13 Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech 

MMP13 Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech
SDP

Catalog No. 501732026 Shop All Proteintech Group Inc Products
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50-173-2026 150 μL
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Catalog No. 50-173-2026 Supplier Proteintech Group Inc Supplier No. 181651AP150UL
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Description

Rabbit Polyclonal Antibody

MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.

Specifications

Antigen MMP13
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MMP13
Gene Accession No. P23097, P33435, P45452
Gene Alias CLG3, Collagenase 3, Matrix metalloproteinase 13, MMP 13, MMP13
Gene Symbols Mmp13, mmp13a
Host Species Rabbit
Immunogen MMP13 Fusion Protein Ag12653
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171052, 17386, 387293, 4322
Target Species Human, Mouse, Rat, Zebrafish
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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