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MMS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
$518.60
Specifications
Antigen | MMS2 |
---|---|
Concentration | 0.41 mg/mL |
Applications | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-172-6516
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Proteintech Group Inc
106891AP150UL |
150 μL |
Each of 1 for $518.60
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Description
The differentiation and activation of monocytes (MO) and monocytic cells is modulated by 1alpha,25-dihydroxyvitamin D3 (Vitamin D3). Recently, using mRNA Differential Display technology, Fritsche J, et al have identified a gene which is induced in freshly isolated human blood MO that are cultured for 4 hours with Vitamin D3 (1). This cDNA encodes a putative 16. 5 kD protein. The product of this gene has structural homology with yeast MMS2p and human CROC-1), which defines a structurally and functionally conserved Ubc-like protein family (2). This protein was called Ubiquitin E2 variant (UBE2V2) or MMS2 (methyl methanesulfonate sensitive 2). The yeast UEV protein, Mms2, is required together with Ubc13 for RAD6/RAD18-dependent postreplicative DNA repair in yeast (3). These proteins also play a central role in the assembly of K63-linked polyubiquitin chains (4,5) UEV/Ubc complexes have been implicated in the assembly of Lys63-linked polyubiquitin chains that act as a novel signal in postreplicative DNA repair and IkBa kinase activation. Recent crystal structure analysis provides direct evidence that the Mms2/Ubc13 heterodimer is necessary for DNA repair (6,7).Specifications
MMS2 | |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
Q15819, Q7M767, Q9D2M8 | |
287927, 70620, 7336 | |
MMS2 Fusion Protein Ag1111 | |
Primary | |
-20°C | |
UBE2V2 |
0.41 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
DDVit 1, DDVIT1, EDAF 1, EDPF 1, EDPF1, MMS2, MMS2 homolog, UB2V2, UBE2V2, UEV 2, UEV2, Vitamin D3 inducible protein | |
Ube2v2 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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