Moesin Antibody (MSN/493), PE/Cy5.5, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP247917PECY55

Catalog No. N247917PEC5

Description

Moesin Monoclonal specifically detects Moesin in Human, Rat (Negative) samples. It is validated for Flow Cytometry, Knockout Validated.

Specifications

• Antigen: Moesin
• Classification: Monoclonal
• Conjugate: PE-Cyanine5.5
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: MSN
• Immunogen: Recombinant full-length human Moesin protein (Uniprot: P26038)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry, Immunoassay
• Clone: MSN/493
• Dilution: Flow Cytometry, Knockout Validated
• Gene Alias: Membrane-organizing extension spike protein, moesin
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Cytoskeleton Markers, Stem Cell Markers
• Gene ID (Entrez): 4478.0
• Target Species: Human, Rat (Negative)
• Isotype: IgG1 κ