Invitrogen™ BODIPY™ 665/676 (Lipid Peroxidation Sensor)

Description

BODIPY 665/676 is a lipophilic probe used to detect lipid peroxidation. It exhibits a change in fluorescence after interaction with peroxyl radicals within cells.

BODIPY 665/676 is a lipophilic probe used to detect lipid peroxidation. It exhibits a change in fluorescence after interaction with peroxyl radicals within cells. We recommend dissolving BODIPY 665/676 in high-quality anhydrous DMSO to attain a stock concentration of 1 to 10 mM.

Lipid peroxidation is the oxidative degradation of cellular lipids by free radicals from reactive oxygen species, which can degrade lipids containing carbon-carbon double bonds such as phospholipids and polyunsaturated fatty acids. Oxidation of lipids leads to the generation of lipid peroxides and can cause damage to cell membranes, resulting in changes to signal transduction pathways and eventually leading to cell death. Lipid peroxidation is involved in apoptosis and one of the main contributors to ferroptosis, an iron-dependent, non-apoptotic form of cell death. Oxidative stress from lipid peroxidation plays a role in aging, as well as pathologies such as cancer, atherosclerosis, and neurodegenerative diseases.

Order Info

Shipping Condition: Room Temperature

Specifications

• Color: Far-red
• Quantity: 5 mg
• For Use With (Application): Cell Analysis, Cell Metabolism, Cell Viability, Proliferation and Function, Nitro-Oxidative Stress, Reactive Oxygen Species
• Shipping Condition: Room Temperature
• Target Function: Lipid peroxidation
• Detection Method: Fluorescence
• Excitation/Emission: 665/676 nm
• Indicator: ROS
• Product Line: BODIPY™
• Product Type: Lipid Sensor

For Research Use Only. Not for use in diagnostic procedures.