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  6. Mouse anti-beta 2-Microglobulin, Clone: SPM374, Novus Biologicals™

Mouse anti-beta 2-Microglobulin, Clone: SPM374, Novus Biologicals™
SDP

Catalog No. NBP24446602 Shop All R&D Systems Products
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0.2 mg
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NBP24446602 0.2 mg
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Catalog No. NBP24446602 Supplier Novus Biologicals Supplier No. NBP2444660.2MG

Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

beta 2-Microglobulin Monoclonal antibody specifically detects beta 2-Microglobulin in Human, Primate (Negative) samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

Antigen beta 2-Microglobulin
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone SPM374
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. P61769
Gene Alias beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Gene Symbols B2M
Host Species Mouse
Immunogen Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.
Molecular Weight of Antigen 12 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 567
Test Specificity Recognizes a protein of 12kDa, identified as b2-microglobulin. Beta-2-microglobulin non-covalently associates with the 44kDa a chain to form the HLA Class I antigen complex. Human beta-2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human b2-microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of beta2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
Target Species Human, Primate (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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For Research Use Only

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