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  6. Mouse anti-c-Myb, Clone: MYB286, Azide Free, Novus Biologicals™

Mouse anti-c-Myb, Clone: MYB286, Azide Free, Novus Biologicals™
SDP

Catalog No. NBP23469002 Shop All R&D Systems Products
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0.2 mg
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NBP23469002 0.2 mg
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Catalog No. NBP23469002 Supplier Novus Biologicals Supplier No. NBP2346900.2 MG

Description

Mouse Monoclonal Antibody

c-Myb Monoclonal antibody specifically detects c-Myb in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, CyTOF-ready.

Specifications

Antigen c-Myb
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, CyTOF
Classification Monoclonal
Clone MYB286
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, CyTOF-ready
Formulation 10mM PBS - BSA free with No Preservative
Gene Accession No. P10242
Gene Alias c-myb, Cmyb, c-myb protein (140 AA), c-myb_CDS, c-myb10A_CDS, c-myb13A_CDS, c-myb14A_CDS, c-myb8B_CDS, efg, Proto-oncogene c-Myb, transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog, v-myb myeloblastosis viral oncogene homolog (avian)
Gene Symbols MYB
Host Species Mouse
Immunogen A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH
Molecular Weight of Antigen 75 kDa
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Cancer, Phospho Specific
Primary or Secondary Primary
Gene ID (Entrez) 4602
Test Specificity The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
Reconstitution Protein A purified
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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