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  6. Mouse anti-CCL16/HCC-4/LEC, Clone: LEC66, Azide Free, Novus Biologicals™

Mouse anti-CCL16/HCC-4/LEC, Clone: LEC66, Azide Free, Novus Biologicals™
SDP

Catalog No. NBP23466602 Shop All R&D Systems Products
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0.2 mg
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NBP23466602 0.2 mg
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Catalog No. NBP23466602 Supplier Novus Biologicals Supplier No. NBP2346660.2 MG

Description

Mouse Monoclonal Antibody

CCL16/HCC-4/LEC Monoclonal antibody specifically detects CCL16/HCC-4/LEC in Human samples. It is validated for ELISA, Functional.

Specifications

Antigen CCL16/HCC-4/LEC
Applications ELISA, Functional Assay
Classification Monoclonal
Clone LEC66
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution ELISA 1-5ug/ml for coating, Functional
Formulation 10mM PBS - BSA free with No Preservative
Gene Accession No. O15467
Gene Alias C-C motif chemokine 16, chemokine (C-C motif) ligand 16, Chemokine CC-4, Chemokine LEC, CKb12, HCC-4Liver-expressed chemokine, LCC-1Lymphocyte and monocyte chemoattractant, LEC, liver CC chemokine-1, LMCSmall-inducible cytokine A16, monotactin-1, MTN-1, NCC4IL-10-inducible chemokine, NCC-4ILINCK, new CC chemokine 4, SCYA16MGC117051, SCYL4, small inducible cytokine subfamily A (Cys-Cys), member 16
Gene Symbols CCL16
Host Species Mouse
Immunogen Recombinant human HCC-4 protein
Molecular Weight of Antigen 11 kDa
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6360
Test Specificity Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelo-suppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones. The ability of HCC-4 to markedly improve recognition of poorly immunogenic cells suggests that it could be an effective component of antitumor vaccines.
Reconstitution Protein A purified
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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